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Ugo Nespolo (born 29 August 1941 in Mosso, Biella) is an Italian painter and sculptor, particularly known for his experimental films, his applied arts works and his artistic collaborations in advertising, theatre and literature. Nespolo graduated at the Accademia Albertina di Belle Arti of Turin with Enrico Paulucci and obtained a degree in Modern Literature at the University of Turin, with a thesis on Semiology.

His career as an artist started in the 1960s and his work was influenced by Pop Art, which was becoming popular in Italy in those years, conceptual art, Arte Povera and Fluxus. he met and appreciated these movements during his frequent trips to the United States. After the first trip in 1967, he regularly visited the States, where he spent long periods especially during the 1980s. Since then, irony and transgression are part of his art and characterise Nespolo's work in the years to come. Since 2010 he has been member of the Honour Committee of Immagine & Poesia, an artistic literary movement founded in Turin, with the patronage of Aeronwy Thomas (Dylan Thomas's daughter). In 2016 he signed the pptArt Manifesto, an international art movement that promote many notable initiatives like the Corporate Art Awards.